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Эпигенетика в медицине

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Apple Academic Press, 2014. — 387 p. — ISBN 978-1-4822-2482-5, 978-1-926895-78-9. This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including: host-pathogen interactions causal relationships between genes and the environment the effects of...
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Academic Press, 2019. — 358 p. — (Translational Epigenetics). — ISBN 978-0-12-813796-3. This book, Volume 12, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship...
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Springer-Verlag, 2014. — 416 p. — (Epigenetics and Human Health). — ISBN 978-3-642-45197-3, 978-3-642-45198-0. Translational aspect: describes how immune cell function is controlled and highlights human diseases where this is dysfunctional From animal models to humans: Describes how more primitive organisms use the epigenetic regulatory machinery and explains what controls the...
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Humana Press, 2018. — 330 p. This indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely...
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Second Edition. — Academic Press, 2019. — 829 p. — ISBN 978-0-12-814067-3. This book, Second Edition, fully examines the causal basis of evolution from an epigenetic point-of-view. By revealing the epigenetic uses of the genetic toolkit, this work demonstrates the primacy of epigenetic mechanisms and epigenetic information in generating evolutionary novelties. The author...
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Academic Press, 2019. — 960 p. — (Translational Epigenetics). — ISBN 978-0-12-813939-4. This book, Volume 10 provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from...
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National Book Network International, Royal Society of Chemistry, 2015. — 336 p. — (RSC drug discovery series). — ISBN 978-1-78262-848-4, 1782628487, 1849738823, 978-1-84973-882-8. Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company and a substantial number of biotechnology companies targeting epigenetic processes to...
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Humana Press, 2018. — 294 p. — (Methods in Molecular Biology 1856). This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics...
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Hoboken, New Jersey: Wiley-Blackwell, 2011. — 418 p. — ISBN 0471710962, 9780471710967, 9781118005743, 9781118005729, 9781118005734. Cancer Epigenetics: Biomolecular Therapeutics in Human Cancer is the only resource to focus on biomolecular approaches to cancer therapy. Its presentation of the latest research in cancer biology reflects the interdisciplinary nature of the field and...
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Springer, 2018. — 92 p. — (Advances in Experimental Medicine and Biology 1012). This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA,...
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Springer, 2013. — 689 p. — (Subcellular Biochemistry 61). — ISBN 978-94-007-4524-7, 978-94-007-4525-4. Role of genome organisation as a basic platform of different epigenetic phenomena in the pathophysiological context Epigenetic regulation of transcription Epigenetic contribution in development Epigenetic mechanisms of important diseases such as diabetes, AIDS, Alzheimer?s...
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Academic Press, 2015. — 520 p. — ISBN 0128009578, 9780128009574. Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs,...
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Springer-Verlag, 2014. — 505 p. — ISBN 978-1-4939-0705-2, 978-1-4939-0706-9. In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including...
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Springer, 2012. — 459 p. The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly...
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Springer-Verlag, 2012. — 465 p. — ISBN 978-1-4614-3344-6, 978-1-4614-3345-3. Patho-Epigenetics is a new discipline, and it’s covered here in detail Written by experts in this exciting new field Brings together recent results of epigenetic research with special attention to disease development In multicellular organisms the establishment, maintenance, and programmed alterations of...
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Academic Press, 2019. — 515 p. — (Translational Epigenetics). — ISBN 978-0-12-814879-2. This book compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians,...
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Elsevier; Academic Press, 2016. — 560 p. The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines...
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Springer International Publishing, 2016. — 264 p. — (Epigenetics and Human Health). — ISBN 978-3-319-24491-4, 978-3-319-24493-8. Comprehensive overview from basic research to application in psychiatry Highlights gene-environment interactions in stress-related psychiatry disorders Including a section on biomarkers in various psychiatric disorders The field of neuroendocrinology has...
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Springer International Publishing, 2016. — 261 p. — (Epigenetics and Human Health). — ISBN 978-3-319-29900-6, 978-3-319-29901-3. Comprehensive overview from basic research to application in psychiatryHighlights gene-environment interactions in stress-related psychiatric disorders Including a section on biomarkers in various psychiatric disorders The field of neuroendocrinology has...
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Academic Press, 2012. — 577 p. — ISBN 978-0-12-388415-2. Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic...
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2nd Edition. — Academic Press, 2018. — 1059 p. — (Translational Epigenetics). — ISBN 978-0-12-812215-0. This book, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role...
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Academic Press, 2016. — 902 p. Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders...
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Academic Press, 2019. — 427 p. — (Translational Epigenetics). — ISBN 978-0-12-814513-5. This book, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA...
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Academic Press, 2018. — 414 p. — (Translational Epigenetics). — ISBN 978-0-12-809912-4. The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the...
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Wiley, 2009. — 465 p. — ISBN 0470758619, 9780470758618. The role of epigenetic mechanisms in autoimmune disease is only now starting to become clear. Understanding these mechanisms, their effect on cellular function and the role of environmental factors is vital to determining how to manage these often debilitating and fatal diseases. Drawing on the research of leading experts,...
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