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Геномика и протеомика

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A John Wiley&Sons, Inc. Publication, 2008. — 818 p. Acronyms and abbreviations An introduction to proteomics: applications to plant biology. Ralph A. Bradshaw Technologies Gel-based proteomics. Pier Giorgio Righetti, Paolo Antonioli, Carolina Simo`, and Attilio Citterio Mass spectrometry-based proteomics: identifying plant proteins. Eveline bergmuёller, Sacha Baginsky,...
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Wiley, 2009. - 325 p. In the last decade DNA sequencing costs have decreased over a magnitude, largely because of increasing throughput by incremental advances in tools, technologies and process improvements. Further cost reductions in this and in related proteomics technologies are expected as a result of the development of new high-throughput techniques and the computational...
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Springer, 2017. — 370 p. — ISBN 4431564527, 9784431564522. This book provides glycoscientists with a handbook of useful databases that can be applied to glycoscience research. Although many databases are now publicly available, one of the hurdles for their users is the learning curve required to effectively utilize those databases. Therefore, this book not only describes the...
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John Wiley & Sons Ltd, 2005. — 269 p. — ISBN 0-470-09439-7 Data Analysis and Visualization in Genomics and Proteomics is the first book addressing integrative data analysis and visualization in this field. It addresses important techniques for the interpretation of data originating from multiple sources, encoded in different formats or protocols, and processed by multiple...
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Academic Press, 2019. — 460 p. — ISBN 978-0-12-814919-5. This book provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover...
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Springer, 2015. — 839 p. The book provides a comprehensive account of the latest trends and developments of omics technologies or approaches and their applications in plant science. Thirty chapters written by 90 experts from 15 countries are included in this state-of-the-art book. Each chapter describes one topic/omics such as: omics in model plants, spectroscopy for plants, next...
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Taylor & Francis Group, 2013. - 695 p. - With the advent of new technologies and acquired knowledge, the number of fields in omics and their applications in diverse areas are rapidly increasing in the postgenomics era. Such emerging fields—including pharmacogenomics, toxicogenomics, regulomics, spliceomics, metagenomics, and environomics—present budding solutions to combat global...
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The Royal Society of Chemistry, 2017. - 427 p. The field of proteomics has developed rapidly over the past decade nurturing the need for a detailed introduction to the various informatics topics that underpin the main liquid chromatography tandem mass spectrometry (LC-MS/MS) protocols used for protein identification and quantitation. Proteins are a key component of any...
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4th Edition. — Garland Science, 2017. — 540 p. — ISBN: 978-0815345084 Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses,...
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4th Edition. — Garland Science, 2017. — 540 p. — ISBN: 978-0815345084 Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses,...
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CRC Press, 2003. - 314 p. Since the advent of cDNA microarrays, oligonucleotide array technology, and gene chip analysis, genomics has revolutionized the entire field of biomedical research. A byproduct of this revolution, toxicogenomics is a fast-rising star within toxicological analysis. Gathering together leading authors and scientists at the forefront of the field, An...
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Springer International Publishing AG 2017. — 256 p. — ISBN 3319615084. In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these "metagenomes". Using the modern tools of genome sequencing and cloning, researchers have now been...
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Royal Society of Chemistry, 2010. — 428 p. This authoritative book provides readers with a comprehensive view of advanced nuclear analytical techniques for metallomics and metalloproteomics. Content: Introduction; Neutron activation analysis; X-ray Fluorescence (XRF); Isotopic techniques combined with ICP-MS and ESI-MS; Mossbauer Spectroscopy; X-ray absorption spectroscopy;...
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Springer Science & Business Media, 2008. — 280 p. Genomics research on animals has generated huge databases and several new concepts and strategies, which are used to elucidate origin, evolution and phylogeny of species. Genetic and physical maps of genomes give details on chromosomal location, function, expression and regulation of genes. The series Genome Mapping and Genomics in...
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Wiley, 2004. — 218 p. Plant research has stood at the forefront of the genomics revolution. One of the first genome projects, the sequencing of the commonly used model organism Arabidopsis, has already yielded important results for the study of a broad array of crops such as corn and soybeans. With crop and food bioengineering only in its infancy, the need to understand the...
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Academic Press; 1st edition (May 13, 2002) 336 pages ISBN-10: 012200731X This book presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the...
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A John Wiley&Sons, Inc., Publication, 2006. – 977 p. (Wiley-Interscience Series In Mass Spectrometry) Oxidatively modified proteins and proteomic technologies Chemical Modification of Proteins by Reactive Oxygen Species Earl R. Stadtman and Rodney L. Levine The Chemistry of Protein Modifications Elicited by Nitric Oxide and Related Nitrogen Oxides Douglas D. Thomas,...
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Springer; 1 edition (December 29, 2008) 356 pages ISBN-10: 0387727167 Combinatorial chemistry is used to find materials that form sensor microarrays. This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions, peptide chemistry, carbodhydrate chemistry,...
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U.S. Department of Energy, 1992. — 44 p. June 1992 DOE Human Genome 1991-92 Program Report. Series: DOE Human Genome Program The primer is intended to be an introduction to basic principles of molecular genetics pertaining to the genome project. Introduction DNA Genes Chromosomes Mapping and Sequencing the Human Genome Mapping Strategies Genetic Linkage Maps Physical...
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Springer, 2007. — 300 p. — ISBN: 978-0387475080, e-ISBN: 978-0387475097. This book aims to present state-of-the-art analytical methods from statistics and data mining for the analysis of high-throughput data from genomics and proteomics. Research and development in genomics and proteomics depend on the analysis and interpretation of large amounts of data generated by...
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Springer, 2015. — 305 p. This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes...
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John Wiley & Sons, 2010. — 328 p. — ISBN: 978-0470163733. Data Mining for Genomics and Proteomics uses pragmatic examples and a complete case study to demonstrate step-by-step how biomedical studies can be used to maximize the chance of extracting new and useful biomedical knowledge from data. It is an excellent resource for students and professionals involved with gene or...
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Springer International Publishing AG, 2017. — 356 p. — ISBN 978-3-319-59824-6. The 14 contributed chapters in this book survey the most recent developments in high-performance algorithms for NGS data, offering fundamental insights and technical information specifically on indexing, compression and storage; error correction; alignment; and assembly. The book will be of value to...
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Springer International Publishing AG, 2017. — 356 p. — ISBN 978-3-319-59824-6. The 14 contributed chapters in this book survey the most recent developments in high-performance algorithms for NGS data, offering fundamental insights and technical information specifically on indexing, compression and storage; error correction; alignment; and assembly. The book will be of value to...
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World Scientific, 2011. — 223 p. — ISBN: 9814327727, 978-9814327725. Series: Science, Engineering, and Biology Informatics (Book 7). Mapping the genomic landscapes is one of the most exciting frontiers of science. We have the opportunity to reverse engineer the blueprints and the control systems of living organisms. Computational tools are key enablers in the deciphering...
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Wiley, 2002. — 297 p. Eric Engel and Stylianos Antonarakis have written the most authoritative and vital reference on molecular and clinical aspects of uniparental disomy (UPD) and genomic imprinting to date. Genomic Imprinting and Uniparental Disomy in Medicine features comprehensive overviews of a multitude of genetic disorders linked to UPD, with a strong emphasis on clinical...
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The Royal Society of Chemistry, UK, 2014. — 390 p. — (New Developments in Mass Spectrometry No.1) — ISBN: 1849738084 As a component of post-genome science, the field of proteomics has assumed great prominence in recent years. Whereas quantitative analyses focussed initially on relative quantification, a greater emphasis is now placed on absolute quantification and consideration of...
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Wiley, 2006. - 541 p. - This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.
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CRC Press, 2014. — 453 p. While functional foods have become a reasonably well-established concept, personalized nutrition is still treated with skepticism by many. The recognition that people would have different nutrient requirements, or perceive foods in different ways, raises several concerns—some real, some not so real. Nutrigenomics and Nutrigenetics in Functional Foods and...
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Springer, 2009. - 453 p. - Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility of DNA to gene regulatory components and the ability of...
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Oxford University Press, 2015. — 288 р. Describes the rapid rise of genomics, and the unprecedented possibilities it brings Sets out the implications for humans: compulsory DNA sequencing of newborns? Your genome snatched from a stray hair? Recounts the latest developments moving from sequencing to the creation of new forms of life Shows how genomics is revealing the...
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Academic Press, 2016. — 328 p. — (Translational epigenetics series). — ISBN 0128001402, 978-0-12-800140-0, 9780128004968, 0128004967. Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics,...
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A John Wiley&Sons, Inc., Publication, 2011. – 412 p. (Wiley-Interscience Series In Mass Spectrometry) General overview: platelets, sample preparation, and mass spectrometry-based proteomics Platelets and Their Role in Thrombotic and Cardiovascular Disease: The Impact of Proteomic Analysis Ronald G. Stanley, Katherine L. Tucker, Natasha E. Barrett, and Jonathan M. Gibbins...
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Springer Science+Business Media, New York, 2016. — 117 p. — ISBN 1493965409. The development of proteomic analyses using advanced mass spectrometry techniques has revolutionized the way proteins are studied, namely, as individual molecules within a complex system. HIV-1 Proteomics: From Discovery to Clinical Application comprehensively covers protein analysis from the early...
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Springer International Publishing AG, 2017. — 379 p. —(Plant Genetics and Genomics: Crops and Models 21) — ISBN 3319493272. Marking the change in focus of tree genomics from single species to comparative approaches, this book covers biological, genomic, and evolutionary aspects of angiosperm trees that provide information and perspectives to support researchers broadening the...
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Elsevier, 2017. — 303 p. — ISBN: 978-0-444-63667-6. This book provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends in the field, compiling the latest ideas from across the entire arena of biotechnology and bioengineering. This volume provides data-based scientific knowledge and state-of-art information on functional genomics...
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John Wiley & Sons, 2004. - 361 p. Contents Preface General Toxicology A Short Introduction to the Expression Profile Toolbox Microarray Manufacture Scanners Databases for Toxicogenomics Statistics for Toxicogenomics Real-Time and Quantitative PCR Confounding Variables and Data Interpretation Introduction to Relationships Between Toxicology and Gene Expression The...
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A John Wiley&Sons, Inc., Publication, 2007. – 404 p. (Wiley-Interscience Series In Mass Spectrometry) Introduction Overview Proteomic Platforms for Biomarkers Discovery Some Existing Cancer Biomarkers Potential Cancer Biomarkers Protein Networks and Protein Phosphorylation in Cancer Ethical Issues and Initiatives Relevant to Cancer Biomarkers Abbreviations Index
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A John Wiley&Sons, Inc., Publication, 2005. – 449 p. Introduction to part 1 Instrumentation and developments Proteomics in cancer research Current strategies for protein quantification Proteomics today: separation science at work Conventional isoelectric focusing in gel matrices and capillaries and immobilized ph gradients Sodium dodecyl sulfate–polyacrylamide gel...
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Wiley-VCH, 2008. — 485 p. — ISBN 978-3-527-31796-7. This long-awaited first guide to sample preparation for proteomics studies overcomes a major bottleneck in this fast growing technique within the molecular life sciences. By addressing the topic from three different angles -- sample, method and aim of the study -- this practical reference has something for every proteomics...
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Intech, 2012. — 275 p. The past decade has seen the field of proteomics expand from a highly technical endeavor to a widely utilized technique. The objective of this book is to highlight the ways in which proteomics is currently being employed to address issues in the biological sciences. Although there have been significant advances in techniques involving the utilization of...
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Massachusetts Institute of Technology Press, 2017. — 343 p. The rise of genomics engendered intense struggle over the control of knowledge. In Reordering Life , Stephen Hilgartner examines the “genomics revolution” and develops a novel approach to studying the dynamics of change in knowledge and control. Hilgartner focuses on the Human Genome Project (HGP)—the symbolic and...
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Kluwer Academic Publishers, 2004. - 395 p. — ISBN: 1-4020-2323-5, ISBN: 1-4020-2322-7. Preface A constancy in human history is that new discoveries have systematically been used to improve health and increase the duration and quality of life. From the use of flints to perform primitive surgery during prehistory, to the preparation of plant extracts to cure diseases throughout...
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Oxford University Press, 2000. — 275 p. With the complete genomes of many organisms now available, and the first draft of the human genome imminent, there is an increasing demand from researchers in a range of disciplines for techniques that will allow them to utilize these resources in their own research. This book provides a comprehensive treatment of the range of methods...
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Elsevier, 2013. - 468 p. - Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of...
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Springer, 2018. - 375 p. - Volume 16 of Translational Bioinformatics. This book elucidates how advances in genomics research are being applied in connection with heart diseases. It describes the development of genome-scale technologies and their applications to all areas of cardiac investigations, such as genomics, functional genomics, epigenomics, etc., and how they relate to a...
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Springer, 2013. - 341 p. - The capacity of the epigenome to interpret both internal and external stimuli and alter expression programs is a critical component in normal development, aging, and disease pathogenesis. In the past decade, we have witnessed an explosion of unprecedented research on and support for epigenetics, epigenomics, and their interface with human health and...
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Springer, 2013. - 308 p. - Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne...
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The MIT Press, 2003. — 241 p. Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in...
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Springer Science & Business Media, 2006. — 560 p. The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics...
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Springer Basel, 2013. — 185 p. This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and...
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Academic Press, 2018. — 296 p. — ISBN 978-0-12-809414-3. This book examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic...
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Wiley, 2013. - 432 p. Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often–neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from...
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Springer, 2014. — 385 p. Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries...
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2nd Edition. — Oxford University Press, 2012. — 420 p. Our genome is the blueprint to our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the...
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CRC Press, 2010. — 404 p. Lab-on-a-chip technology permits us to make many important discoveries that can only be observed at the microscale or the nanoscale. Using this technology, biological and biochemical analyses translate into greater sensitivity, more accurate results, and more valuable findings. Authored by one of the field’s pioneering researchers, Fundamentals of...
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Humana Press Inc., 2002. — 198 p. Daniel C. Liebler masterfully introduces the science of proteomics by spelling out the basics of how one analyzes proteins and proteomes, and just how these approaches are then employed to investigate their roles in living systems. He explains the key concepts of proteomics, how the analytical instrumentation works, what data mining and other...
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Cambridge University Press, 2009. — 444 p. Recombinant Antibodies for Immunotherapy provides a comprehensive overview of the field of monoclonal antibodies (mAbs), a market that has grown tremendously in recent years. Twenty-five articles by experienced and innovative authors cover the isolation of specific human mAbs, humanization, immunogenicity, technologies for improving...
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Norfolk, UK: Caister Academic Press, 2017. — 263 p. — ISBN 1910190551. In this era of the "Green Planet", cyanobacteria are ideally placed for exploitation as microbial cell factories, both for carbon capture and storage and for the sustainable production of secondary metabolites and biofuels. The application of omics technologies to cyanobacterial research has yielded a wealth of...
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Wiley, 2017. - 674 p. The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, major...
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John Wiley & Sons, Ltd, 2002. — 241 р. Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology. This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of...
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John Wiley & Sons, Ltd, 2002. — 241 р. Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology. This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of...
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Academic Press, 2007. — 276 p. This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. The book presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author...
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Wiley-VCH, 2006. — 395 p. — ISBN 3-527-31757-0. On the cutting edge of medical diagnostics, plasma proteomics promises to generate a new wave of technologies to help identify many different diseases and disease risks. Plasma and serum are the preferred non-invasive specimens to test normal individuals, at-risk groups, and patients for protein biomarkers discovered and validated to...
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CRC Press, Taylor & Francis Group, 2010. — 419 p. — ISBN: 978-1420076585. Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to...
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CRC Press, 2018. — 217 p. This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology. Controlling the Biogenesis of the Smallest Regulators Computational...
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Wiley, 2009. - 806 p. - This volume provides up–to–date information on all major families of metal–binding proteins, including their structural, physico–chemical, and functional properties. After an introduction to cation binding, it discusses methods for the investigation of the binding of different cations to proteins. Then it gives characteristics of Ca–binding proteins,...
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Wiley, John & Sons, 2003. — 800 p. Introduction to Bioinformatics provides a broad-based introduction to bioinformatics by following three, real-world examples throughout the book: retinol-binding protein, breast cancer, and a calcium binding site C 2. The author emphasizes the use of computational tools and databases to study connections between the structure of proteins and...
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Wiley, John & Sons, 2009. — 971 p. Introduction to Bioinformatics provides a broad-based introduction to bioinformatics by following three, real-world examples throughout the book: retinol-binding protein, breast cancer, and a calcium binding site C. The author emphasizes the use of computational tools and databases to study connections between the structure of proteins and genes...
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Wiley, John & Sons, 2009. — 971 p. Introduction to Bioinformatics provides a broad-based introduction to bioinformatics by following three, real-world examples throughout the book: retinol-binding protein, breast cancer, and a calcium binding site C. The author emphasizes the use of computational tools and databases to study connections between the structure of proteins and genes...
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3rd Edition. - Wiley, 2015. - 1161 p. - The bestselling introduction to bioinformatics and genomics – now in its third edition. Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for...
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Woodhead Publishing, 2015. — 337 p. The book reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, investigating epigenetic modifications and epigenetic memory through analysis of DNA methylation states, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental...
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Springer, 2015. — 221 p. Entomology as a science of inter-depended branches like molecular entomology, insect biotechnology, has made rapid progress. This also implies that there is an urgent need to manage the available resources. In the past five decades, entomology has taken giant steps ahead. The aim of this work is to integrate perspectives across molecular and biochemistry,...
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Springer, 2016. — 272 p. Entomology is a super science, embracing interdisciplinary approaches in genomics, proteomics, and interdependent fields of biochemistry, physiology, molecular entomology, and biotechnology. An urgent need to manage available resources for the benefit of the planet and humankind has led to remarkable progress since publication of the fruit fly genome in...
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2nd Edition. — Wiley, 2012. — 315 p. Molecular Analysis and Genome Discovery, Second Edition is a completely revised and updated new edition of this successful book. The text provides a comprehensive overview of recent developments in the fast moving field of molecular based diagnostics of disease markers. Key concepts and applications are provided alongside practical...
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Duke University Press, 2015. - 294 pp. Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our...
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Humana Press, 2018. — 265 p. — ISBN 1493989030, 9781493989034. This volume provides methods to study bone morphogenetic proteins (BMPs) and BMP modulators in cell culture, in both invertebrate and vertebrate animal models, and for therapeutic applications. Chapters guide the reader in the use of primary and immortalized cell lines, methodologies that exploit transcription and...
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Wiley, 2003. — 427 p. This comprehensive reference covers the comparative methodology involved in studying molecular evolution. Providing a practical introduction to the role of bioinformatics in comparative genomics, this publication further discusses the basic technology used in genome sequencing projects and provides an overview of genome storage databases currently in use.
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Springer, 2013. — 476 p. This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for...
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Wiley-VCH Verlag GmbH & Co. KGaA, 2004. — 435 p. — ISBN 9783527601561. In this first book to provide an overview of applications of proteomics in the discovery of new diagnostic, prognostic and therapeutic targets, a team of international specialists from research institutions, hospitals and companies contribute with their specific expertise. They cover a wide range of example...
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  • 5,44 МБ
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Taylor & Francis Group, 2007. - 474 p. - Facilitating the innovation, development, and application of new spectroscopic methods in proteomics, Spectral Techniques in Proteomics provides a broad overview of the spectroscopic toolbox that can be used, either with proteome or sub-proteome mixtures or with individual/purified proteins studied in parallel. It gives a modest overview of...
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Wiley, 2002. - 418 p. Provides an overview of the rapidly evolving field of genomics with coverage of nucleic acid technologies, proteomics and bioinformatics. It includes chapters on applications in human health, agriculture and comparative genomics and also contains two chapters on the legal and ethical issues of genomics, a topic that is becoming increasingly important as...
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WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2005. — 634 p. — ISBN: 3527313486 In this unique presentation of a revolutionary field of science, the first section introduces the domains of application for genomics and bioinformatics, such as sequencing and the comparative sequence analysis of model organisms, investigating genetically influenced diseases, the...
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Cambridge University Press, 2015. - 228 p. - The study of bacterial genetics has revolutionised with the development of genome sequencing, which let us catalogue the gene content of various clinically and industrially important bacteria and opened up the field of comparative genomics. The research findings on bacterial genetics were further enhanced by the development of allied...
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3rd Edition. - Wiley, 2013. - 510 p. DNA technology is evolving rapidly, with new methods and a fast-growing vocabulary. This unique dictionary offers current, detailed and accessible information on DNA technology to lecturers, researchers and students throughout the biomedical and related sciences. The third edition is a major update, with over 3000 references from mainstream...
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Pearson Education, 2011. — 225 p. — ISBN: 978-0-13-216814-4 In Investigating the Human Genome, leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most...
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Pearson Education, 2011. — 403 p. — ISBN: 9780132172806 In Investigating the Human Genome, leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most...
  • №87
  • 432,72 КБ
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A John Wiley&Sons, Inc., Publication, 2008. – 274 p. (Wiley-Interscience Series In Mass Spectrometry) Introduction Overview of Proteomics Proteomic Tools for Analysis of Cellular Dynamics Dynamics of Functional Cellular Machinery: From Statics to Dynamics in Proteomic Biology Index
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Apple Academic Press, 2015. - 425 p. - The book provides scope and knowledge on advanced techniques and its applications into the modern fields of biotechnology―genomics and proteomics. In this book, different genomics and proteomics technologies and principles are examined. The fundamental knowledge presented in this book opens up an entirely new way of approaching DNA chip...
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  • 18,67 МБ
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Garland Science, 2004. — 350 p. — (Advanced Texts). — ISBN-10 1859962734; ISBN-13 978-1859962732. Principles of Proteomics is designed specifically to explain the different stages of proteomic analysis, their complexities and their jargon to students and researchers in a non-technical overview of the field. The author describes the broad range of problems which proteomics can...
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  • 26,62 МБ
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Springer London, 2010. — 270 p. Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and...
  • №91
  • 33,10 МБ
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2nd Edition. — Wiley-Blackwell, 2019. — 335 p. — ISBN 978-1-119-08172-2. Building on the strength of the original edition, this book presents the state of the art in the field of proteomics and offers students and scientists new tools and techniques to advance their own research. Written by leading experts in the field, it provides readers with an understanding of new and emerging...
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  • 6,70 МБ
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Wiley, 2006. - 336 p. Written by recognized experts in the study of proteins, Proteomics for Biological Discovery begins by discussing the emergence of proteomics from genome sequencing projects and a summary of potential answers to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are then dealt with in terms of underlying...
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Wiley, 2007. — 329 p. This is the definitive, core reference on metabolome analysis for research scientists in biochemistry and analytical chemistry, as well as academics, researchers, and technicians in the fields of functional genomics and metabolic engineering. It is also a practical text for scientists working to discover metabolites from natural sources and for graduate...
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Springer, 2015. — The field of clinical proteomics has rapidly evolved during the past few years and is continuously growing as new methodologies and technologies emerge. In Clinical Proteomics, a select group of leading researchers has contributed their state-of-the-art methodologies on protein profiling and identification of disease biomarkers in tissues, microdissected cells...
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  • 8,33 МБ
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Springer Netherlands, 2013. — 394 p. “Bioinformatics of Human Proteomics” discusses the development of methods, techniques and applications in the field of protein bioinformatics, an important direction in bioinformatics. It collects contributions from expert researchers in order to provide a practical guide to this complex field of study. The book covers the protein interaction...
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Humana Press, 2014 — 333p. — (Methods in Molecular Biology 1107) — ISBN: 978-1-62703-748-8 (eBook), 978-1-62703-747-1 (Hardcover). In miRNomics: MicroRNA Biology and Computational Analysis , expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective. These include methods and...
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2nd Edition. — Springer Science+Business Media, Inc., 2006. — 426 pages The 2nd edition of this book adds 8 new contributors to reflect a modern cutting edge approach to genomics. The expanded scope includes coverage of statistical issues on single nucleotide polymorphism analysis array, CGH analysis, SAGE analysis, gene shaving and related methods for microarray data analysis,...
  • №98
  • 12,50 МБ
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KLUWER ACADEMIC PUBLISHERS, 2002. — 356 pages ISBN: 1402070233 At the beginning of the post-sequencing era, biology must now work with the enormous amounts of quantitative data being amassed and must render complex problems in mathematical terms, with all of the computational effort that entails. This phenomenon is perhaps best exemplified by the interdisciplinary...
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  • 5,74 МБ
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McGraw-Hill, 2001. — 288 p. This text provides a behind-the-scenes look at the sequencing of the human genome project and the birth of the science of genomics. It explains genomics as an information science and traces its history back further than standard histories and news accounts to the early visionaries who saw the gene as as information carrier. It covers the early protein...
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  • 1004,45 КБ
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Пермь: Перм. ун-т., 2008. — 120 с. — ISBN 978-5-7944-1231-4 Монография посвящена одному из самых перспективных инновационных направлений развития современной биологической науки - биотехнологии, а именно ее первой и основополагающей части - геномике. Рассматриваются научно-методические основы молекулярно-генетической паспортизации и идентификации редких и находящихся под...
  • №101
  • 1,89 МБ
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Учебно-методическое пособие. — Минск: БГМУ, 2008. — 28 с. Рассмотрены наиболее часто используемые в эволюционной биохимии и молекулярной эволюции методы определения характера аминокислотных замен. Приведен пример применения данных методов для решения прикладных задач. Предназначено для студентов 1-го курса всех факультетов, слушателей факультативного курса «Молекулярная эволюция»,...
  • №102
  • 2,06 МБ
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М.: Мир, 1990. — 246с., ил. ISBN 5-03-001846-8 Сборник молекулярно-биологических методов, используемых при изучении генома человека, написанный коллективом авторов из США и Великобритании. Изложению каждого метода предшествует краткое теоретическое введение, что делает доступной для начинающих исследователей. Описаны методы трансфекции эукариотических клеток; рестрикционное...
  • №103
  • 20,28 МБ
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Учеб. метод. пособие. — Н. Новгород: Изд-во ННГУ, 2007. — 86 с. В пособии представлены современные биоинформационные аспекты протеомики и деградации белка. Представлены базы данных по протеомике, методы и примеры использования баз данных в молекулярно-биологических исследованиях. Детально описываются молекулярные механизмы регулируемой деградации белка и их роль в жизни клетки...
  • №104
  • 1,05 МБ
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Учебное пособие. — СПб.: Лань, 2009. — 80 с. — ISBN 978-5-8114-0977-8 (Учебники для вузов. Специальная литература). Учебное пособие по основам полимеразной цепной реакции предназначено для студентов ветеринарно-биологического факультета и факультета ветеринарной медицины очной, очно-заочной (вечерней) и заочной форм обучения, факультета повышения квалификации в период изучения...
  • №105
  • 2,76 МБ
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М.: Либроком, 2009. — 304 с. Предлагаемая читателю книга посвяшена рассмотрению актуальной проблемы современной генетики — изучению и расшифровке геномов (определению полной структуры ДНК) живых организмов, включая геном человека. Полная информация о фундаментальных открытиях в этой области доступна в основном узким специалистам по публикациям в научных журналах, преимущественно...
  • №106
  • 18,99 МБ
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Учебное пособие. — Ростов-на-Дону: Изд-во ЮФУ, 2010. — 60 с. В учебном пособии представлены новые направления постгеномной эры развития молекулярной биологии и генетики. Основное внимание уделено обобщению опыта авторов и анализу данных отечественной и зарубежной литературы по характеристике новой фундаментальной концепции названной «протеом», призванной радикально прояснить...
  • №107
  • 965,32 КБ
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