Файл содержит материалы, опубликованные в журнале "Annual Review of Pharmacology and Toxicology", Volume 44, 2004 г. Predicting human drug glucuronidation parameters: Application of in vitro and in silico modeling approaches. Oxidative stress, toxicology, and pharmacology of CYP2E1. The identification of ligands at orphan g-protein coupled receptors. Biochemical mechanism of nitroglycerin action and tolerance: Is this old mystery solved? Developmental neuropathology of environmental agents. The integration of pharmacokinetics and pharmacodynamics: Understanding dose-response Transporters and renal drug elimination Identification of the major steps in botulinum toxin action ERBB receptors: directing key signaling networks throughout life Novel angiogenic signaling pathways and vascular targets The role of oxidative stress in carcinogenesis DARPP-32: An Integrator of Neurotransmission ß-adrenergic receptors and regulation of energy expenditure: a family affair Protein sulfenic acids in redox signaling The role of calpain in oncotic cell death Voltage-gated sodium channels and hyperalgesia Neurogenesis in the adult brain: new strategies for central nervous system diseases Muscarinic acetylcholine receptor knockout mice: Novel phenotypes and clinical implications Mixed-lineage kinases: a target for the prevention of neurodegeneration Analysis of gaba receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics Sex differences in pharmacokinetics and pharmacodynamics CRF and CRF receptors: role in stress responsivity and other behaviors Membrane trafficking of g protein-coupled receptors
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