Schlucker S., Kiefer W. Surface Enhanced Raman Spectroscopy: Analytical, Biophysical and Life Science Applications

Wiley-VCH, 2011. - 331 p.
Covering everything from new developments in the field to established techniques with a focus on biochemical applications, this monograph shows how to analyze surface characteristics right down to single molecules.
From the contents:Theory and practice of available surface-enhanced Raman scattering (SERS) substrates
Analytical applications
SERS combined with other analytical techniques
Biophysical applications
Microscopic applications and related techniquesIn the 14 chapters of this book, an authoritative, up-to-date account of the principles and fundamentals of SERS is given including many examples for its applications. The book includes the basic theory for SERS; summarizes the various SERS substrates; discusses quantitative SERS methods with emphasis on reproducibility, stability and sensitivity up to single molecule detection;
and describes SERS microscopy, electrochemical SERS, surface enhanced resonance Raman scattering (SERRS), and surface-enhanced hyper Raman scattering (SEHRS), as well as surface- and tip-enhanced coherent anti-Stokes Raman scattering (SE-CARS, TE-CARS). Applications of SERS include the detection of organic pollutants and pharmaceuticals; studies of electron transfer of proteins at membrane models; investigations of microfluidics, quantitative DNA analysis, biomedical applications by means of SERS microscopy, SERS as an intracellular probe; and coupling of SERS with various separation methods (e.g. liquid or gas chromatography).Hands-on knowledge for analytical, surface and medicinal chemists, spectroscopists, biophysicists and materials scientists.