Deps Patrícia D. (ed.) Hansen’s Disease: A Complete Clinical Guide

Springer, 2023. — 323 p. — ISBN 978-3-031-30893-2.Hansen’s disease (leprosy) is endemic in more than 100 countries worldwide, with over 200,000 new diagnoses each year and more than 4 million people living with some form of HD-related impairment. The World Health Organization’s ‘Global Leprosy Strategy’ timeline for Hansen’s disease elimination indicates that it will be encountered in clinical practice in endemic countries for at least another decade. Increasing north-to-south migration, global travel and overseas medical work mean that physicians in non-endemic countries will also encounter patients with Hansen’s disease, which can affect people for many years before diagnosis and after treatment. For busy clinicians, it represents a challenge, in terms of disease learning and updating knowledge and skills.This book provides a concise, up-to-date, and comprehensive source of information on Hansen’s disease clinical practice. It covers essential topics on all clinical aspects, complemented by history, epidemiology, paleopathology, and the social impact of the disease. Edited and written by contributors with decades of experience, it’s divided into twenty-six chapters clarifying the genetics and neurological manifestations, physical disabilities and its prevention; oral, ophthalmological, and bone changes, among others.For the primary audience of practicing physicians, it is an affordable point of reference, whilst also being suitable for student and trainee doctors. It’s also accessible to general practitioners and specialists in dermatology, neurology, pediatrics, infectious disease, family and community medicine, and orthopedics, as well as to non-specialists and other healthcare professionals.Introduction to Hansen’s Disease
The Journey to a Scientific Understanding of Leprosy: A Brief Outline
The Origin, Evolution and History of Leprosy Through a Palaeopathological Lens
Hansen’s Disease and Human Rights
Leprosy Agents and Principal Methods of Detection, Identification, and Characterization of the Leprosy Agents
Epidemiology of Hansen’s Disease
Hansen’s Disease and One Health
Metabolic, Genetic and Immunological Mechanisms in Susceptibility to Leprosy
Clinical Aspects and Classification of Hansen’s Disease
Reactions in Hansen’s Disease
Hansen’s Disease in Children
Neuropathophysiology in Morbus Hansen or Hansen’s Disease: Mechanisms of Nerve Injury
Neurological Alterations In Hansen’s Disease
Evaluation, Monitoring and Prevention of Disabilities in Hansen’s Disease
Ophthalmological Alterations in Hansen’s Disease
Ear, Nose, Throat, and Mouth Alterations in Hansen’s Disease
Osteoarticular Alterations in Hansen’s Disease
Diagnostic Imaging in Hansen’s Disease: Conventional Radiography, Computed Tomography, Magnetic Resonance Imaging, and Dual-Energy X-Ray Absorptiometry
Co-infection and Immunosuppression in Hansen’s Disease
Differential Diagnosis of Cutaneous Lesions of Hansen’s Disease
Differential Diagnoses of the Neurological Manifestations of Hansen’s Disease
Immune and Chemoprophylaxis in Hansen’s Disease
Psychosocial Aspects of Hansen’s Disease
Peripheral Nerve by Ultrasound in Hansen’s Disease
Electroneuromyography in Hansen’s Disease
Treatment of Hansen’s Disease