Urigüen Leyre, Díez-Alarcia Rebeca (eds.) Schizophrenia: Methods and Protocols

Humana Press, 2023. — 160 p. — (Methods in Molecular Biology 2687). — ISBN 978-1-0716-3306-9.This volumes presents current methods used in the research of schizophrenia. Chapters guide readers through molecular techniques, in vivo approaches, cell cultures and heterologous expression systems, and even research methods involving human studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Schizophrenia: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.A Novel Method to Estimate Levels of Receptors Using an Allosteric Modulator:​ Focus on Muscarinic M1 Receptor
Enhanced Bystander BRET (ebBRET) Biosensors as Biophysical Tools to Map the Signaling Profile of Neuropsychiatric​ Drugs Targeting GPCRs
[35S]GTPγS (Guanosine-5′-O-(γ-thio)triphosphate-[35S]) Binding Scintillation Proximity Assay Experiments in Postmortem Brain Tissue
CRISPR/​Cas9 as a Simple Technique for the Generation of Murine Knockout Models for Neuropsychiatric​ Diseases
Evaluation of Sensorimotor Gating Deficits in Mice Through Prepulse Inhibition (PPI) of the Startle Response
Automated Detection of Psychedelic-Induced Head-Twitch Response in Mice
Gastrointestinal​ and Microbiome Profiling in Rodent Models of Neurological and Psychiatric Disorders
Electroencephalo​graphy for the Study of the Auditory P300 Evoked Potential and Derived Measurements
Quantification of Endocannabinoids​ in Human Plasma
Neuropsychologic​al and Functional Assessment of Cognitive Impairments in Schizophrenia
Clinical Management and Assessment of the Early Stages of Psychosis:​ A Multidimensional​ Approach