Mavromoustakos T., Tzakos A.G., Durdagi S. (eds.) Supramolecules in Drug Discovery and Drug Delivery: Methods and Protocols

Springer, 2021. — 344 p. — (Methods in Molecular Biology 2207). — ISBN: 978-1-0716-0919-4.This detailed book aims to provide readers with critical information to accomplish the synthesis of nanosystems for the purpose of supramolecular entities complexing with drugs, targeted drug delivery system characterization, as well as the study of the physical-chemical interactions that govern the stability and properties of these systems. Beginning with a collection of chapters on drug delivery platforms such as cyclodextrins, micelles, liposomes, polymeric, nanotubes, and more, the volume continues with coverage of the study of nanotechnology systems using different biophysical techniques such as DSC, ITC, solid and liquid NMR spectroscopy, and electrochemistry. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Supramolecules in Drug Discovery and Drug Delivery: Methods and Protocols serves as an ideal guide for researchers working toward drug delivery mechanisms that can tailor their physical chemical properties and enhance their efficacy, while retaining their structures intact.Application of Neutralization and Freeze-Drying Technique for the Preparation of the Beneficial in Drug Deliverydelivery 2-Hydroxypropyl-β-Cyclodextrin Complexes with Bioactive Molecules
Functionalized Carbon Nanohorns as Drug Deliverydelivery Platforms
Ultrasonics-Assisted Effective Isolation and Characterization of Exosomes from Whole Organs
Aggregate Determination by Permeation Technique
Study of Candesartan Cilexetil: 2-Hydroxypropyl-β-Cyclodextrin Interactions: A Computational Approach Using Steered Molecular Dynamics Simulations
Drug Deliverydelivery: Hydrophobic Drug Encapsulation into Amphiphilic Block Copolymer Micelles
Multisensitive Polymeric Nanocontainers as Drug Deliverydelivery Systems: Biological Evaluation
Drug Incorporation in the Drug Delivery System of Micelles
Molecular Dynamics Protocols for the Study of Cyclodextrin Drug Deliverydelivery Systems
Drug Delivery Through Multifunctional Polypeptidic Hydrogels
Polymersomes from Hybrids -Polypeptides for Drug Deliverydelivery Applications
Drug Delivery Systems Based on Modified Polysaccharides: Synthesis and Characterization
Differential Scanning Calorimetry (DSC) on Sartan/Cyclodextrin Delivery Formulations
Encapsulation of Small Drugs in a Supramolecule Enhances Solubility, Stability, and Therapeutic Efficacy Against Glioblastoma Multiforme
Unveiling the Thermodynamic Aspects of Drug-Cyclodextrin Interactions Through Isothermal Titration Calorimetry
Antitumor Efficacy of Ceranib-2 with Nano-Formulation of PEG and Rosin Esters
Association of the Thermodynamics with the Functionality of Thermoresponsive Chimeric Nanosystems
2D DOSY NMR: A Valuable Tool to Confirm the Complexation in Drug Deliverydelivery Systems
Drug-Encapsulated Cyclodextrin Nanosponges
Electrochemistry Investigation of Drugs Encapsulated in Cyclodextrins
A Differential Scanning Calorimetry (DSC) Experimental Protocol for Evaluating the Modified Thermotropic Behavior of Liposomes with Incorporated Guest Molecules
Applications of NMR in Drug:Cyclodextrin Complexes
Construction of Peptide-Drug Conjugates for Selective Targeting of Malignant Tumor Cells