Langman Loralie J., Snozek Christine L.H. (eds.) LC-MS in Drug Analysis: Methods and Protocols

2nd edition. — Humana Press, 2019. — 270 p. — (Methods in Molecular Biology 1872). — ISBN: 978-1-4939-8822-8.This second edition provides detailed LC-MS(/MS) procedures for the analysis of compounds of clinical and toxicological significance. Chapters detail new and updated methods for analyzing drugs focusing on advances in technology, alternate matrices, and rapidly-changing classes of drugs of abuse, compounds pertinent to toxicology, and therapeutic agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, LC-MS in Drug Analysis: Methods and Protocols, Second Edition aims to ensure successful reults in the further study of this vital field.An Introduction to Drug Testing: The Expanding Role of Mass Spectrometry
Quantification of Eight Cannabinoids Including Cannabidiol in Human Urine Via Liquid Chromatography Tandem Mass Spectrometry
Analysis of Benzodiazepines for Drug-Facilitated Assaults and Abuse Settings (Urine)
Targeted Opioid Screening Assay for Pain Management Using High-Resolution Mass Spectrometry
Measurement of Buprenorphine and Norbuprenorphine in Urine
Quantitation of Tapentadol by Liquid Chromatography: Tandem Mass Spectrometry
Therapeutic Drug Monitoring of Lacosamide by LC-MS/MS
LC-MS/MS Method for the Quantification of the Leflunomide Metabolite, Teriflunomide, in Human Serum/Plasma
Analysis of Tryptic Peptides from Therapeutic Monoclonal Antibodies Using LC-MS/MS
Quantification of Methotrexate in Human Serum and Plasma by Liquid Chromatography Tandem Mass Spectrometry
Simultaneous Determination of Tacrolimus and Cyclosporine A in Whole Blood by Ultrafast LC-MS/MS
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method to Quantify Gabapentin and Pregabalin in Urine
The Evolving Landscape of Designer Drugs
Analysis of Synthetic Cannabinoid Metabolites by Liquid Chromatography-Tandem Mass Spectrometry
Quantification of Designer Opioids by Liquid Chromatography–Tandem Mass Spectrometry
Screening Analysis for Designer Stimulants by LC-MS/MS
Drug Screening Using Liquid Chromatography Quadrupole Time-of-Flight (LC-QqTOF) Mass Spectrometry
Alternate Matrices: Meconium, Cord Tissue, Hair, and Oral Fluid
Salt-Assisted Liquid-Liquid Extraction of Meconium for Analysis of Cocaine and Amphetamines by Liquid Chromatography-Tandem Mass Spectrometry
Detection of In Utero Cannabis Exposure in Umbilical Cord Tissue by a Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method
Quantitation of Ethyl-β-d-Glucuronide in Human Umbilical Cord Tissue by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Analysis of Drugs in Oral Fluid Using LC-MS/MS
Determination of Cocaine and Metabolites in Dried Blood Spots by LC-MS/MS