Perez-Lloret Santiago (ed.) Clinical Trials In Parkinson's Disease

Humana Press, 2021. — 396 p. — (Neuromethods 160). — ISBN: 978-1-0716-0911-8.This volume looks at major clinical trials for motor and non-motor symptoms in Parkinson’s Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection. Chapters in this book discuss topics such as toxin-based rodent or genetic models of PD; clinical trials for motor symptoms, L-DOPA related motor complications, and gait disorders; clinical trials for mood disorders, troubled sleep, autonomic dysfunction; and clinical trials for disease modifying therapies. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory or research center. Cutting-edge and authoritative, Clinical Trials in Parkinson’s Disease is a valuable resource for clinicians and researchers who want to enhance their interpretation of results from clinical trials and to design their own high-quality trials.Preclinical Models of Parkinson’s Disease
Toxin-Based Rodent Models of Parkinson’s Disease
Assessment of Nonmotor Symptoms in Rodent Models of Parkinson’s Disease
Genetic Models of Parkinson’s Disease
Clinical Trials for Motor Symptoms in Parkinson’s Disease
A Review of Randomized Phase III Pharmacological Clinical Trials for Motor Symptoms in Parkinson’s Disease Patients and Quality of Evidence Recommendations
Clinical Trials for Motor Complications in Parkinson’s Disease
Clinical Trials for Gait Disorders in Parkinson’s Disease
Clinical Trials for Disease-Modifying Agents in Parkinson’s Disease
Value and Methods of Pharmacovigilance in the Monitoring of Drug Safety in Parkinson’s Disease
Clinical Trials for Nonmotor Symptoms in Parkinson’s Disease
Clinical Trials for Cognitive Impairment and Dementia in Parkinson’s Disease
Clinical Trials for Depression, Anxiety, Fatigue, and Apathy in Parkinson’s Disease
Clinical Trials for Sleep Disorders and Daytime Somnolence in Parkinson’s Disease
Clinical Trials on Management of Pain in Parkinson’s Disease
Clinical Trials for Orthostatic Hypotension in Parkinson’s Disease and Other Synucleinopathies
Clinical Trials for Erectile Dysfunction in Parkinson’s Disease
Clinical Trials for Constipation in Parkinson’s Disease