The Royal Society of Chemistry, 2020. — 629 p. — ISBN 978-1-78801-214-0.Continuous crystallization is an area of intense research, with particular respect to the pharmaceutical industry and fine chemicals. Improvements in continuous crystallization technologies offer chemical industries significant financial gains, through reduced expenditure and operational costs, and consistent product quality. Written by well-known leaders in the field, The Handbook of Continuous Crystallization presents fundamental and applied knowledge, with attention paid to application and scaling up, and the burgeoning area of process intensification. Beginning with concepts around crystallization techniques and control strategies, the reader will learn about experimental methods and computational tools. Case studies spanning fine and bulk chemicals, the pharmaceutical industry, and employing new mathematical tools, put theory into context. Contents Nucleation and Crystal Growth in Continuous Crystallization Fundamentals of Population Balance Based Crystallization Process Modeling Continuous Crystallisation With Oscillatory Baffled Crystalliser Technology Process Control Slug-flow Continuous Crystallization: Fundamentals and Process Intensification Continuous Crystallization of Bulk and Fine Chemicals Process Intensification in Continuous Crystallization Continuous Membrane Crystallization Process Analytical Technology in Continuous Crystallization Continuous Protein Crystallization Continuous Melt Crystallization Continuous Enantioselective Crystallization of Chiral Compounds Continuous Isolation of Active Pharmaceutical Ingredients Continuous Eutectic Freeze Crystallization Economic Analysis of Continuous Crystallisation Digital Design and Operation of Continuous Crystallization Processes via Mechanistic Modelling Tools
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