Hussein W.M., Skwarczynski M., Toth I. (Ed.) Peptide Synthesis: Methods and Protocols

Springer Science+Business Media, 2020. — 337 p. — (Methods in Molecular Biology 2103). — ISBN: 978-1-0716-0226-3.This book provides a variety of procedures for synthetically producing peptides and their derivatives, ensuring the kind of precision that is of paramount importance for successful synthesis. Numerous techniques relevant to drugs and vaccines are explored, such as conjugation and condensation methodologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Peptide Synthesis: Methods and Protocols serves as an essential guide to the many crucial processes that will allow researchers to efficiently prepare, purify, characterize, and use peptides for chemical, biochemical, and biological studies.Solution Phase Peptide Synthesis: The Case of Biphalin
Application of Fmoc-SPPS, Thiol-Maleimide Conjugation, and Copper(I)-Catalyzed Alkyne-Azide Cycloaddition “Click” Reaction in the Synthesis of a Complex Peptide-Based Vaccine Candidate Against Group A Streptococcus
In Situ Neutralization Protocols for Boc-SPPS
Anhydrous Hydrogen Fluoride Cleavage in Boc Solid Phase Peptide Synthesis
Automated Solid-Phase Peptide Synthesis
New Developments in Microwave–Assisted Solid Phase Peptide Synthesis
Protecting Groups in Peptide Synthesis
Synthesis of O-Acyl Isopeptides: Stepwise and Convergent Solid-Phase Synthesis
An Isodipeptide Building Block for Microwave-Assisted Solid-Phase Synthesis of Difficult Sequence-Containing Peptides
SPOT Synthesis: The Solid-Phase Peptide Synthesis on Planar Surfaces
Solid-Phase Synthesis of Wollamide Cyclohexapeptide Analogs
Synthesis of Branched Peptides via a Side-Chain Benzyl Ester
Solid-Phase Synthesis of Octapeptin Lipopeptides
Peptidomimetic Synthesis: Drug Discovery for Alzheimer’s Disease
Synthesis of Amide Backbone-Modified Peptides
Synthesis of NickFects, a New Family of CPPs, by Solid-Phase Peptide Synthesis
Chemoenzymatic Synthesis of HIV-1 Glycopeptide Antigens
Synthesis of Antimicrobial Lipopeptides Using the “CLipPA” Thiol-Ene Reaction
Decarboxylative Couplings for Late-Stage Peptide Modifications
Peptide and Pseudopeptide Bond Synthesis in Phosphorus Dipeptide Analogs
Microbioreactor Techniques for the Production and Spectroscopic Characterization of Microbial Peptides
Metal–Peptide Complexes to Study Neurodegenerative Diseases