Becker W. (Ed.) Advanced Time-Correlated Single Photon Counting Applications

Springer, 2015. — 639 p. — (Springer Series in Chemical Physics 111). — ISBN: 978-3-319-14928-8.This book is an attempt to bridge the gap between the instrumental principles of multi-dimensional time-correlated single photon counting (TCSPC) and typical applications of the technique. Written by an originator of the technique and by sucessful users, it covers the basic principles of the technique, its interaction with optical imaging methods and its application to a wide range of experimental tasks in life sciences and clinical research.
The book is recommended for all users of time-resolved detection techniques in biology, bio-chemistry, spectroscopy of live systems, live cell microscopy, clinical imaging, spectroscopy of single molecules, and other applications that require the detection of low-level light signals at single-photon sensitivity and picosecond time resolution.Introduction to Multi-dimensional TCSPC
TCSPC FLIM with Different Optical Scanning Techniques
Fluorescence Lifetime Imaging (FLIM): Basic Concepts and Recent Applications
Determination of Intracellular Chloride Concentrations by Fluorescence Lifetime Imaging
Calcium Imaging Using Transient Fluorescence-Lifetime Imaging by Line-Scanning TCSPC
Imaging Cell and Tissue O2 by TCSPC-PLIM
FRET Microscopy: Basics, Issues and Advantages of FLIM-FRET Imaging
Monitoring HIV-1 Protein Oligomerization by FLIM FRET Microscopy
Unraveling the Rotary Motors in FoF1-ATP Synthase by Time-Resolved Single-Molecule FRET
Partitioning and Diffusion of Fluorescently Labelled FTY720 in Resting Epithelial Cells
Probing Microsecond Reactions with Microfluidic Mixers and TCSPC
An Introduction to Interpreting Time Resolved Fluorescence Anisotropy Curves
Time-Resolved Spectroscopy of NAD(P)H in Live Cardiac Myocytes
Fluorescence Lifetime Measurements of NAD(P)H in Live Cells and Tissue
Fluorescence Lifetime Imaging of the Skin
Fluorescence Lifetime Imaging in Ophthalmology
Dynamic Mapping of the Human Brain by Time-Resolved NIRS Techniques
Time-Domain Diffuse Optical Imaging of Tissue by Non-contact Scanning
Breast Monitoring by Time-Resolved Diffuse Optical Imaging
Errata to: Advanced Time-Correlated Single Photon Counting Applications
Erratum to: Fluorescence Lifetime Imaging (FLIM): Basic Concepts and Recent Applications