Springer, 2019. — 295 p. — ISBN: 978-3-030-15393-9
This book describes a practical approach to the diagnosis, management, and prevention of infectious complications in solid-organ transplant (SOT) candidates and recipients, based on both up-to-date clinical evidence and state of the art expert opinion from world-renowned experts in the field. The book is divided into three parts, the first of which explains risk assessment and the general approach to infectious diseases in the pre-, peri-, and early and late post-transplant periods. The remaining two sections address the prevention and treatment of infection with particular pathogens and the management of specific syndromes, such as pneumonia, CNS infections, UTIs, and skin infections.Infections in SOT recipients – often due to multidrug-resistant organisms – represent a major challenge. Preventive strategies need to be adapted according to the type of allograft and period after transplantation. Moreover, toxicity and drug interaction with immunosuppressive drugs must be taken into consideration when treating infectious complications. In explaining in depth how best to ensure allograft and patient survival, this book will be of value to infectious disease specialists and transplant physicians at all levels of experience.
General Transplant Infectious DiseasesThe Epidemiology of Infection in Solid Organ Transplant Recipients: A Practical Timeline
Risk Assessment of Infections in SOT Recipients
Pre- and Peri-transplant Period: Screening and Treatment of Infections in the Pretransplant Period, Donor-Derived Infection
Prevention of Bacterial, Viral, Fungal, and Parasitic Infections During the Early Post-transplant Period
Late Posttransplant Period: Posttransplant Vaccination, Travel Advice, Foodborne Infections
Specific PathogensPrevention and Treatment of CMV Infection (and Other Herpes Viruses)
Prevention and Treatment of EBV-Related Complications
Prevention and Treatment of Polyomavirus-Associated Diseases
Prevention and Treatment of Respiratory Virus Infection
Prevention and Treatment of Viral Hepatitis
Multidrug-Resistant Organisms in Solid Organ Transplantation
Prevention and Treatment of Mold Infections
Prevention and Treatment of Yeast and Endemic Fungal Infections
Prevention and Treatment of Mycobacterial Infections
Prevention and Treatment of Other Opportunistic Infections: Nocardiosis, Toxoplasmosis, Chagas and Pneumocystis Disease
Management of Specific SyndromesPneumonia in Solid Organ Transplant Recipients
Management of CNS Infections
Management of Urinary Tract Infection
Management of Infections of Devices: Catheter-Related Infections, Pretransplant VAD Infections, Infections of ECMO Devices
Management and Prevention of Skin Infections