London, UK: Oneworld Publications Ltd., 2018. — 286 p. — ISBN 1786074362.A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene. Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science. Contents An Unexpected Change of Plans in America Stumbling into the Ribosome Seeing the Invisible The First Crystals of the Machine Going to the Mecca of Crystallography Emerging from the Primordial Mist A Threshold Is Crossed The Race Begins Getting Started in Utah Return to Mecca Coming Out of the Closet Almost Missing the Boat The Final Assault Seeing the New Continent The Politics of Recognition The Ribosome Road Show The Movie Emerges The Phone Call in A Week in Stockholm Science Marches On
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