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Wong Chi-Huey (ed.) Carbohydrate-based Drug Discovery (2 Volume-Set)

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Wong Chi-Huey (ed.) Carbohydrate-based Drug Discovery (2 Volume-Set)
Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2003. - 956 p. - ISBN 3-527-30632-3.
To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential.
Topics include the following:
Chemical Synthesis of Carbohydrates
Carbohydrate Biosynthesis and Metabolism
Carbohydrate Analysis
Cellular Functions of Carbohydrates
Development of Carbohydrate-based Drugs
A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists.
Volume 1
Complex Carbohydrate Synthesis
The Chemistry of Sialic Acid
Solid-Phase Oligosaccharide Synthesis
Solution and Polymer-supported Synthesis of Carbohydrates
Enzymatic Synthesis of Oligosaccharides
Glycopeptides and Glycoproteins: Synthetic Chemistry and Biology
Chemistry and Biochemistry of Asparagine-linked Protein Glycosylation
Conformational Analysis of C-Glycosides and Related Compounds
Synthetic Lipid A Analogs for Sepsis Treatment
Polysialic Acid Vaccines
Synthetic Carbohydrate-based Vaccines
Antithrombotics Based on Synthetic Oligosaccharides
Volume 2
Sequencing of Oligosaccharides and Glycoproteins
Analytical Techniques for the Characterization and Sequencing of Glycosaminoglycans
Synthetic Multivalent Carbohydrate Ligands as Effectors or Inhibitors of Biological Processes
Glycosyltransferase Inhibitors
RNA-Aminoglycoside Interactions
Glycosylated Natural Products
Small Molecule Inhibitors of the Sulfotransferases
Carbohydrate-based Treatment of Cancer Metastasis
N-Acetylneuraminic Acid Derivatives and Mimetics as Anti-influenza Agents
Carbohydrate-based Drug Discovery in the Battle Against Bacterial Infections
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