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Salway J.G. (ed.) Metabolism at a Glance

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Salway J.G. (ed.) Metabolism at a Glance
4th edition. — Wiley-Blackwell, 2017. — 148 p.
Fully updated and extensively illustrated, this new edition of Metabolism at a Glance is now in full colour throughout, and includes new coverage of sports biochemistry; the metabolism of lipids, carbohydrates and cholesterol; glyceroneogenesis, α-oxidation and ω-oxidation of fatty acids. It also features the overlooked “Krebs Uric Acid Cycle”.
Energy metabolism
Introduction to metabolic pathways
Biosynthesis of ATP I: ATP, the molecule that powers metabolism
Biosynthesis of ATP II: mitochondrial respiratory chain
Oxidation of cytosolic NADH: the malate/aspartate shuttle and glycerol phosphate shuttle
Metabolism of glucose to provide energy
Metabolism of one molecule of glucose yields 31 (or should it be 38?) molecules of ATP
Anaerobic metabolism of glucose and glycogen to yield energy as ATP
2,3-Bisphosphoglycerate (2,3-BPG) and the red blood cell
Metabolism of triacylglycerol to provide energy as ATP
Carbohydrate metabolism
Metabolism of glucose to glycogen
Glycogen metabolism I
Glycogen metabolism II
Glycogen metabolism III: regulation of glycogen breakdown (glycogenolysis)
Glycogen metabolism IV: regulation of glycogen synthesis (glycogenesis)
Pentose phosphate pathway: the production of NADPH and reduced glutathione
Regulation of glycolysis: overview exemplified by glycolysis in cardiac muscle
Glycolysis in skeletal muscle: biochemistry of sport and exercise
Regulation of gluconeogenesis
Regulation of Krebs cycle
Mammals cannot synthesize glucose from fatty acids
Supermouse: overexpression of cytosolic PEPCK in skeletal muscle causes super-athletic performance
Sorbitol, galactitol, glucuronate and xylitol
Fructose metabolism
Ethanol metabolism
Fat metabolism
Pyruvate/malate cycle and the production of NADPH
Metabolism of glucose to fat (triacylglycerol)
Metabolism of glucose to fatty acids and triacylglycerol
Glycolysis and the pentose phosphate pathway collaborate in liver to make fat
Esterification of fatty acids to triacylglycerol in liver and white adipose tissue
Mobilization of fatty acids from adipose tissue I: regulation of lipolysis
Mobilization of fatty acids from adipose tissue II: triacylglycerol/fatty acid cycle
Glyceroneogenesis
Metabolism of protein to fat after feeding
Elongation and desaturation of fatty acids
Fatty acid oxidation and the carnitine shuttle
Ketone bodies
Ketone body utilization
p-Oxidation of unsaturated fatty acids
Peroxisomal p-oxidation
a- and p-oxidation
co-Oxidation
Steroid metabolism
Cholesterol
Steroid hormones and bile salts
Amino acid metabolism
Biosynthesis of the non-essential amino acids
Catabolism of amino acids I
Catabolism of amino acids II
Metabolism of amino acids to glucose in starvation and during the period immediately after refeeding
Disorders of amino acid metabolism
Phenylalanine and tyrosine metabolism
Tryptophan metabolism: the biosynthesis of NAD+, serotonin and melatonin
Ornithine cycle for the production of urea: the ‘urea cycle’
Metabolic channelling
Metabolic channelling I: enzymes are organized to enable channelling of metabolic intermediates
Metabolic channelling II: fatty acid synthase
Purines, pyrimidines and porphyrins
Amino acid metabolism, folate metabolism and the ‘1-carbon pool’ I: purine biosynthesis
Amino acid metabolism, folate metabolism and the ‘1-carbon pool’ II: pyrimidine biosynthesis
Krebs uric acid cycle for the disposal of nitrogenous waste
Porphyrin metabolism, haem and the bile pigments
Integration of metabolic pathways and diabetes
Metabolic pathways in fasting liver and their disorder in Reye’s syndrome
Diabetes I: metabolic changes in diabetes
Diabetes II: types I and II diabetes, MODY and pancreatic p-cell metabolism
Diabetes III: type 2 diabetes and dysfunctional liver metabolism
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