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Brunton Laurence L., Hilal-Dandan Randa, Knollmann Björn C. (eds.) Goodman & Gilman's: The Pharmacological Basis of Therapeutics

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Brunton Laurence L., Hilal-Dandan Randa, Knollmann Björn C. (eds.) Goodman & Gilman's: The Pharmacological Basis of Therapeutics
13th edition. — McGraw-Hill Education / Medical, 2017. — 1438 p.
Thirteenth Edition represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman’s careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease more than 500 color illustrations, with many new figures emphasizing mechanisms of drug action. More than 30 new contributors have added to this edition, while the focus on basic principles is undiminished.
Contributors.
Preface.
Acknowledgments.
General Principles.
Drug Invention and the Pharmaceutical Industry.
Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and.
Elimination.
Pharmacodynamics: Molecular Mechanisms of Drug Action.
Drug Toxicity and Poisoning.
Membrane Transporters and Drug Response.
Drug Metabolism.
Pharmacogenetics.
Neuropharmacology.
Neurotransmission: The Autonomic and Somatic Motor Nervous Systems.
Muscarinic Receptor Agonists and Antagonists.
Anticholinesterase Agents.
Nicotine and Agents Acting at the Neuromuscular Junction and Autonomic Ganglia.
Adrenergic Agonists and Antagonists.
Hydroxytryptamine (Serotonin) and Dopamine.
Neurotransmission in the Central Nervous System.
Drug Therapy of Depression and Anxiety Disorders.
Pharmacotherapy of Psychosis and Mania.
Pharmacotherapy of the Epilepsies.
Treatment of Central Nervous System Degenerative Disorders.
Hypnotics and Sedatives20. Opioids, Analgesia, and Pain Management.
General Anesthetics and Therapeutic Gases.
Local Anesthetics.
Ethanol.
Drug Use Disorders and Addiction.
Modulation of Pulmonary, Renal, and Cardiovascular Function.
Drugs Affecting Renal Excretory Function.
Renin and Angiotensin.
Treatment of Ischemic Heart Disease.
Treatment of Hypertension.
Therapy of Heart Failure.
Antiarrhythmic Drugs.
Treatment of Pulmonary Arterial Hypertension.
Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs.
Drug Therapy for Dyslipidemias.
Inflammation, Immunomodulation, and Hematopoiesis.
Introduction to Immunity and Inflammation.
Immunosuppressants and Tolerogens.
Immune Globulins and Vaccines.
Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor.
Pharmacotherapy of Inflammation, Fever, Pain, and Gout.
Histamine, Bradykinin, and Their Antagonists.
Pulmonary Pharmacology.
Hematopoietic Agents: Growth Factors, Minerals, and Vitamins.
Hormones and Hormone Antagonists.
Introduction to Endocrinology: The Hypothalamic-Pituitary Axis.
Thyroid and Antithyroid Drugs.
Estrogens, Progestins, and the Female Reproductive Tract.
Androgens and the Male Reproductive Tract46. Adrenocorticotropic Hormone, Adrenal Steroids, and the Adrenal Cortex.
Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia.
Agents Affecting Mineral Ion Homeostasis and Bone Turnover.
Gastrointestinal Pharmacology.
Pharmacotherapy for Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux.
Disease.
Gastrointestinal Motility and Water Flux, Emesis, and Biliary and Pancreatic Disease.
Pharmacotherapy of Inflammatory Bowel Disease.
Chemotherapy of Infectious Diseases.
General Principles of Antimicrobial Therapy.
Chemotherapy of Malaria.
Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis,
Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections.
Chemotherapy of Helminth Infections.
Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones,and Agents for Urinary Tract.
Infections.
Penicillins, Cephalosporins, and Other β-Lactam Antibiotics.
Aminoglycosides.
Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents.
Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy.
Antifungal Agents.
Antiviral Agents (Nonretroviral).
Treatment of Viral Hepatitis (HBV/HCV).
Antiretroviral Agents and Treatment of HIV Infection.
Pharmacotherapy of Neoplastic Disease.
General Principles in the Pharmacotherapy of Cancer.
Cytotoxic Drugs.
Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and.
Various Small Molecules.
Hormones and Related Agents in the Therapy of CancerSection IX: Special Systems Pharmacology.
Ocular Pharmacology.
Dermatological Pharmacology.
Environmental Toxicology: Carcinogensand Heavy Metals.
Appendices.
Principles of Prescription Order Writing and Patient Compliance.
Design and Optimization of Dosage Regimens: Pharmacokinetic Data.
Index.
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