Bizzarri M. Systems Biology

Humana Press, 2018. — 382 p. — ISBN: 978-1-4939-7456-6
Series: Methods in Molecular Biology, № 1702There are many definitions striving to capture the hidden meaning of “Systems Biology.” Indeed, despite many efforts, the concept of Systems Biology remains quite uncertain. As already highlighted, currently two primary streams can be recognized within Systems Biology: (1) pragmatic Systems Biology, which emphasizes the use of large-scale molecular interactions (“omic” approach), aimed at building huge signaling networks by applying mathematical modeling, and thus showing how cells make decisions based on the “information” flowing through their networks. (2) Theoretic Systems Biology which posits that the theoretical (and consequently the methodological) basis of biological study should be deeply modified.