Demchenko A.P. Introduction to Fluorescence Sensing

2nd Edition. — Springer International Publishing, Switzerland, 2015. — 818 p. — ISBN: 9783319207797.The fi eld of molecular sensing is immense. It is nearly the whole world of natural and synthetic compounds that have to be analyzed in a broad variety of conditions and for a broad variety of purposes. In the human body, we need to detect and quantify virtually all the genes (genomics) and the products of these genes (proteomics). In our surrounding there is a need to analyze a huge number of compounds including millions of newly synthesized products. Among them, we have to select potentially useful compounds (e.g. drugs) and discriminate those that are ineffi cient and harmful. No less important is to control agricultural production and food processing. There is also a practical necessity to provide control in industrial product technologies, especially in those that produce pollution. Permanent monitoring is needed to maintain safety of our environment. Protection from harmful microbes, clinical diagnostics and control of patient treatment are the key issues of modern medicine. New problems and challenges may appear with the advancement of human society in the twenty-first century. We have to be ready to meet them.Basic Principles
Theoretical Aspects
Fluorescence Detection Techniques
Molecular-Size Fluorescence Emitters
Nanoscale Fluorescence Emitters
Fluorescent Nanocomposites
Recognition Units
Mechanisms of Signal Transduction
Supramolecular Structures and Interfaces Designed for Sensing
Non-conventional Generation and Transformation of Response
The Sensing Devices.
Focusing on Targets
Sensing Inside the Living Cells
Sensing the Whole Body and Clinical Diagnostics
Opening New Horizons
Epilogue
Appendix: Glossary of Terms Used in Fluorescence-Luminescence Sensing