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Tollefsbol T. (Ed.) Personalized epigenetics

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Tollefsbol T. (Ed.) Personalized epigenetics
Elsevier Academic Press, 2015. — 591 p. — (Translational Epigenetics Series). — ISBN 9780124201354, 0124201350.
Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy.
The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field, it also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics. View more >
Discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures
Details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the consequent diagnostic, prognostic and therapeutic potential of the field
Reviews the impact of the environment on epigenetic variations among individuals and the roles of pharmacology and drug development
Devotes several chapters to the advances made in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management
Readership
Advanced undergraduate students, graduate students, health care professionals, university researchers, and pharmaceutical and biotechnology companies interested in drug development. This book could also serve as a core textbook for advanced university or professional school courses with a focus on genetic and/or human diseases
Preface
Overview
Epigenetic variations Among Individuals
Bioinformatics of Personalized Epigenetics
Diagnostic and Prognostic Epigenetic Approaches to Personalized Medicine
Environmental Personalized Epigenetics
Pharmacology and Drugdevelopment of Personalized Epigenetics
Personalized Epigenetics of Disorders and Disease Management
Challenges and Future Directions
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