Academic Press, 1986. — 939 p. — ISBN: 978-0-12-182029-9 Methods in Enzymology 129Methodology development has played a central role in understanding the structure, biosynthesis, and physiological functions of the plasma lipoproteins. The ultracentrifuge played a major role in the discovery and characterization of the plasma lipoproteins, and the instrument continues to be a methodologic mainstay. One result has been a progressively better appreciation of the metabolic interrelationships of the different plasma lipoprotein species. The exciting state of growth in lipoprotein research, the complete lack of a recent comprehensive treatise on the central methodology presently being used in the field, and the relatively limited treatment of lipoproteins in earlier volumes of Methods in Enzymology warranted the assembly of this two-volume work. Volume 128, Part A, deals with the preparation, structure, and molecular biology of the plasma lipoproteins; Volume 129, Part B, deals with the characterization, cell biology, and metabolism of the plasma lipoproteins. These volumes should serve as convenient handbooks for all investigators involved in lipoprotein research.
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