Bondanza A., Casucci M. (Eds.) Tumor Immunology. Methods and Protocols

Humana Press, 2016 — 165p. — (Methods in Molecular Biology 1393) — ISBN: 978-1-4939-3338-9 (eBook), 978-1-4939-3336-5 (Hardcover).This volume explores the still undiscovered secrets of tumor immunology and cancer immunology by discussing the methods and techniques that world-renowned experts in the field use in their laboratories. This book provides a better understanding of the rules governing tumor and cancer immunology, and discusses innovations in the technology of the immunological “smart bullets” (monoclonal antibodies, vaccines, tumor-reactive T cells) used to specifically target cancer cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and cutting-edge, Tumor Immunology: Methods and Protocols contains a wide breadth of subject coverage that any scientist, clinician, or industry professional interested in this field will find valuable.ATMPs for Cancer Immunotherapy: A Regulatory Overview
Natural Antibodies to Tumor-Associated Antigens
Generation and Cryopreservation of Clinical Grade
Quantitative and Qualitative Analysis of Tumor-Associated CD4
Detection and Functional Analysis of Tumor-Derived LXR Ligands
In Vitro Generation of Antigen-Specific T Cells from Induced Pluripotent Stem Cells of Antigen-Specific T Cell Origin
Chimeric Antigen Receptors for Cancer Immunotherapy
Cancer and Chemokines
T Cells as Antigen Carriers for Anti-tumor Vaccination
Exploiting Secreted Luciferases to Monitor Tumor Progression In Vivo
Efficient RNA Interference of Primary Leukemic Cells for Loss-of-Function Studies in Xenograft Mouse Models
Modeling Human Graft-Versus-Host Disease in Immunocompromised Mice
ICOS Expression as Immunologic Marker in Immune Activating Monoclonal Antibodies
Identifying NK Alloreactive Donors for Haploidentical Hematopoietic Stem Cell Transplantation
Human Microtumors Generated in 3D: Novel Tools for Integrated In Situ Studies of Cancer Immunotherapies