Hoffman R.M. (Ed.) Bacterial Therapy of Cancer. Methods and Protocols

Humana Press, 2016 — 186p. — (Methods in Molecular Biology 1409) — ISBN: 978-1-4939-3515-4 (eBook), 978-1-4939-3513-0 (Hardcover).This volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for recise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory
protocols, and tips on troubleshooting and avoiding known pitfalls.
Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.Tumor-Targeting Salmonella typhimurium A1-R: An Overview
Enhancement of Tumor-Targeted Delivery of Bacteria with Nitroglycerin Involving Augmentation of the EPR Effect
Oral Delivery of Tumor-Targeting Salmonella to Treat Cancer in Mice
Microfluidic Device to Quantify the Behavior of Therapeutic Bacteria in Three-Dimensional Tumor Tissue
Tumor-Targeting Therapy Using Gene-Engineered Anaerobic-Nonpathogenic Bifidobacterium longum
Noninvasive In Vivo Imaging to Follow Bacteria Engaged in Cancer Therapy
In Vivo Bioluminescence Imaging of Intratumoral Bacteria
Employment of Salmonella in Cancer Gene Therapy
Development of a Targeted Gene-Delivery System Using Escherichia coli
Isolation and Analysis of Suppressor Mutations in Tumor-Targeted msbB Salmonella
Determination of Plasmid Segregational Stability in a Growing Bacterial Population
Visualization of Anticancer Salmonella typhimurium Engineered for Remote Control of Therapeutic Proteins
Methods for Tumor Targeting with Salmonella typhimurium A1-R
Salmonella typhimurium A1-R and Cell-Cycle Decoy Therapy of Cancer
Future of Bacterial Therapy of Cancer