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Ekinci D. (ed.) Chemical Biology

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Ekinci D. (ed.) Chemical Biology
2nd Edition. - InTech, 2015. - 444 p. - This book contains an overview focusing on the research area of protein purification, enzymology, vitamins, antioxidants, biotransformation, gene delivery, signaling, regulation and organization. Particular emphasis is devoted to both theoretical and experimental aspects.
The textbook is written by international scientists with expertise in synthetic chemistry, protein biochemistry, enzymology, molecular biology, drug discovery and genetics many of which are active chemical, biochemical and biomedical research.
The textbook is expected to enhance the knowledge of scientists in the complexities of chemical and biological approaches and stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of chemical biology.
Contents
Part 1 Protein Purification & Enzymology
Protein Purification
The Problems Associated with Enzyme Purification
Nicotinamide Phosphoribosyltransferase Inhibitors
Cofactor Recycling Using a Thermostable NADH Oxidase
Analyses of Sequences of (p/a) Barrel Proteins Based on the Inter-Residue Average Distance Statistics to Elucidate Folding Processes
Functional Implication Guided by Structure- Based Study on Catalase - Peroxidase (KatG) from Haloarcula Marismortui
Part 2 Vitamins & Antioxidants
Effects of Dietary Fortification of Vitamin A and Folic Acid on the Composition of Chicken Egg
Mitochondria and Antioxidants: The Active Players in Islet Oxidative Stress
Nitric Oxide Signaling During Senescence and Programmed Cell Death in Leaves
Menaquinone as Well as Ubiquinone as a Crucial Component in the Escherichia coli Respiratory Chain
Part 3 Biotransformation & Gene Delivery
Genetically Modified Baker's Yeast Saccharomvces cerevisiae in Chemical Synthesis and Biotransformations
Animal Models for Hydrodynamic Gene Delivery
Part 4 Hormones and Receptors
Role of p-Arrestins in Endosomal Sorting of G Protein-Coupled Receptors
Structure and Function of the Lipolysis Stimulated Lipoprotein Receptor
Ghrelin. a Gastric Hormone with Diverse Functions
Part 5 Organization & Regulation
Polysialylation of the Neural Cell Adhesion Molecule: Setting the Stage for Plasticity Across Scales of Biological Organization
What Does Maurocalcine Tell Us About the Process of Excitation-Contraction Coupling?
13C-Metabolic Flux Analysis and Metabolic Regulation
QCM as Cell-Based Biosensor
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